Name：Xin Jige
Professional title：Professor / PhD
Research focus：Veterinary Public Health
Tutor category：£PhD Supervisor RMaster Supervisor £Neither
E-mail address：1104263681@qq.com
Education
(1) Sep 2011-Dec 2014: Jilin University, China; Biochemistry and Molecular Biology; PhD.
(2) Sep 2004 - July 2007: Yunnan Agricultural University, China; Animal Genetics, Breeding and Reproduction Science; Master.
(3) Sep 2000 - July 2004: Liaoning Normal University, China; Biological Science, Bachelor.
Career
(1) Dec 2019- Aug 2020: College of Veterinary Medicine, Virginia Polytechnic Institute and State University; Visiting Scholar.
(2) Oct 2022- Present: College of Veterinary Medicine,Yunnan Agricultural University, China; Professor.
(3) Oct 2016- Oct 2022: College of Veterinary Medicine,Yunnan Agricultural University, China; Associate Professor.
(4) Nov 2015-Oct 2016: College of Animal Science and Technology, Yunnan Agricultural University, China; Lecturer.
(5) July 2009 - Nov 2015: College of Animal Science and Technology, Yunnan Agricultural University, China; Experimenter.
(6) July 2007 - July 2009: College of Animal Science and Technology, Yunnan Agricultural University, China; Assistant Experimenter.
Courses
(1) Veterinary Public Health
(2) Public Health
(3) Animal Food Safety and Veterinary Public Health
Research focus
(1) Gene Expression and Regulation
(2) Food safety of Animal Origin
(3) Veterinary Public Health
Research & Teaching
Research projects
(1) The Program of Yunnan High-level Talents, Young Talents, (YNWR-QNBJ-2020-154), From Dec 2020 to Dec 2025, 500 000 Yuan, in Research, Presider.
(2) National Natural Science Foundation of China (NSFC), District Fund Projects, 31960658,Generation of Conditional Knockout Pigs via CRISPR/Cas and Blastocyst Complementation in One-step Process, From Jan 2020 to Dec 2023, 400 000 Yuan, Finished, Presider.
(3) National Natural Science Foundation of China (NSFC), District Fund Projects, 31360532, Generation Skin Graft Model of Porcine by TALENs Technology and the Multi-Transgenic Coordinate Expressin Technology via 2A Petide, From Jan 2014 to Dec 2017, 520 000 Yuan, Finished，Presider.
(4) Yunnan Province Science and Technology Department, Applied Basic Research Project, 2013FB041, Study on Multi-gene Modified Pig Model for skin graft, From Sep 2013 to Sep 2016, 100 000 Yuan, Finished，Presider.
Teaching projects
(1) Yunnan Provincial Academic Degree Committee Office, the project of teaching case base construction for professional degree postgraduate in Yunnan Province, July 2022 to June 2025, 15 000 Yuan, in Research, Presider.
(2) Yunnan Agricultural University, China;University-level first-class undergraduate courses, the Course of Veterinary Public Health, 2024, in Research, Presider.
(3) Yunnan Agricultural University, China; Undergraduate education and teaching reform research project, YNAUJG2023081, Reform and practice of the teaching method of Veterinary Public Health with students as the main body of teaching activities, Aug 2023 to Aug 2025, 5 000 Yuan, in Research, Presider.
(4)Yunnan Agricultural University, China; ideological and political education reform project, YAUKCSZJG0038, Ideological and political design and practice in the Course of Veterinary Public Health, May 2022 to May 2024, 2 000 Yuan, finished, Presider.
(5)Yunnan Agricultural University, China; the educational reform project, YNDKJY16-03, practice of participatory teaching in the course of animal food hygiene, Sep 2016 to Sep 2018, 10 000 Yuan, Finished, Presider.
Awards & Honors
(1) Xin Jige(1/1), Chose and Fostered in the Support Plan of Yunnan High-level Talents Training, Young Talents, Yunnan Provincial Human Resources and Social Security Department, 2020.
(2) Xin Jige(1/1), Chose and Fostered in the program of Kunming Younger Subject Leaders and Reserves, 2018.
(3) Xin Jige(1/1), Selected as Young Technological Expertise and Academic Leader, Yunnan Agricultural University, 2016.
(4) Xin Jige(7/10), Innovation of Pig Cloning and Gene Modification Technology and its Application in Biomedical model, Science and Technology Award Commission of Jilin Province, Scientific Progress Awards, First Prize, 2017.
(5) Xin Jige(1/1), Advanced Teacher of Hongyun Gardener Award, Yunnan Agricultural University, 2016.
Representative achievements
Journal Publications
(1) Xin J，He L, Li Y, Pu Q, Du X, Ban F, Han D. Sanguinarine chloride hydrate mitigates colitis symptoms in mice through the regulation of the intestinal microbiome and metabolism of short-chain fatty acids.·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2025,1871(2), 167579.
(2) Xin J, Dong J, Li J, Ye L, Zhang C, Nie F, Gu Y, Ji X, Song Z, Luo Q, Ai J, Han D. Current knowledge on epizootic haemorrhagic disease in China. Vaccines (Basel). 2023,11(6):1123.
(3) Gu Y, Dong J, Li J, Luo Q, Dong X, Tang G, Zhang J, Du X, Pu Q, He L, Zhao K, Han D, Xin J. Antibacterial activity and mechanism of sanguinarine against staphylococcus aureus by interfering with the permeability of the cell wall and membrane and inducing bacterial ROS production. Frontiers in Veterinary Science, 2023, 10:1121082.
(4) Xin J, Lan S, Ai J, Zeng B, Xin A, Ye L, Zuo W, Li Y, Han D. Risk assessment and prevention of foot-and-mouth disease transmission from Laos to China. Veterinary Sciences, 2025, 12(2), 92.
(5) Han D, Yang H, Li J, Zhang C, Ye L, Dong J, Zhang C, Guo R, Xin J. Macleaya cordata extract improves growth performance, immune responses and anti-inflammatory capacity in neonatal piglets. Veterinary Microbiology, 2024, 293, 110090.
(6) Chen C, Han D, Li J, Ye L, Ji X, Nie F, Song Z, Luo Q, Shi Y, Pu Q, Ai J, Xin J. TaqMan real-time RT-PCR assay with an internal amplification control for rapid detection of Bluetongue virus. Med. Weter. 2024,80 (2):68-76.
(7) Han D, Yang H, Che L, Zhang C, Li J, Ye L, Zhang C, Gu R, Xin J. Macleaya cordata extract inhibits LPS-induced IPEC-J2 inflammation through TLR4-mediated NF-κB and MAPK signaling pathways. Natural Product Communications, 2024, 19(4): 1-12.
(8) Shi Y, Han D, Li J, Ye L, Ji X, Nie F, Song Z, Chen C, Ai J, Xin J. A novel quantitative real-time PCR with the GAPDH reference gene for peste des petits ruminants.Veterinarni Medicina, 2024,69(7):234-242.
(9) Xin J, Pu Q, Wang R, Gu Y, He L, Du X, Tang G, Han D. Antibacterial activity and mechanism of chelerythrine against Streptococcus agalactiae. Frontiers in Veterinary Science,2024,11:1408376.
(10) Han D, Ren T, Yang Y, Li Z, Du X, Zhang C, Pu Q, He L, Zhao K, Guo R, Xin J. Application and substitution of antibiotics in animal feeding.Med. Weter. 2024, 80 (1):5-11.
(11) Han D, Yang Y, Li J , Li Z , He L, Pu Q, Du X, Zhao K, Guo R, Xin J. Biological activity of Macleaya cordata and its application in pig industry. Med. Weter. 2024, 80 (3), 103-110.
(12) Xin J, Dai X, Dong J, Zhang C, Yang YQ, Ai J, Han D. Serological surveillance for FMDV antibodies serotypes O and A in cattle in Tongliao, Inner Mongolia, China. Med Weter, 2022, 78(8): 376-382.
(13) Han D, Yang H, Yang Y, Ye L, Dong J, Zhang C, Zhu H, Yin S, Dong X, Su F, Xin J, Ai J. Porcine reproductive and respiratory syndrome virus (PRRSV) antibody levels in large swine farms in selected regions of Yunnan p rovince, China, Med Weter, 2021, 77(10): 497-501.
(14) Zhou X, Xin J, Fan N, Zou Q, Huang J, Ouyang Z, Zhao Y, Zhao B, Liu Z, Lai S, Yi X, Guo L, Miguel A, Zeng Y, Yang H, Lai L. Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer,Cellular and Molecular Life Sciences, 2015, 72(6):1175-1184.
(15) Cheng W, Zhao H, Yu H, Xin J, Wang J, Zeng L, Yuan Z, Qing Y, Li H, Jia B, Yang C, Shen Y, Zhao L, Pan W, Zhao H, Wang W, Wei H. Efficient generation of GGTA1-null Diannan miniature pigs using TALENs combined with somatic cell nuclear transfer. Reproductive Biology and Endocrinology, 2016,14(1):77.
(16) Zou Q, Wang X, Liu Y, Ouyang Z, Long H, Wei S, Xin J, Zhao B, Lai S, Shen J, Ni Q, Yang H, Zhong H, Li L, Hu M, Zhang Q, Zhou Z, He J, Yan Q, Fan N, Zhao Y, Liu Z, Guo L, Huang J, Zhang G,Ying J, Lai L, Gao, X. Generation of gene-target dogs using CRISPR/Cas9 system. Journal of Molecular Cell Biology. 2015, 7(6):580-583.
(17) Xin J, Yang H, Fan N, Zhao B, Ouyang Z, Liu Z, Zhao Y, Li X, Song J, Yang Y, Zou Q, Yan Q, Zeng Y, Lai L. Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs, PLos One, 2013,8(12): e84250.
(18) Zhou S, Han D, Dong J, Yang Y, Ye L, Li J, Zhang C, Xin J. Establishment and application of real-time fluorescence quantitative RT-PCR for detection of BVDV Genotype 1. Journal of Yunnan Agricultural University (Natural Sciences), 2023, 38 (03): 423-430. (in Chinese)
(19) Zhang J, Han D, Shi Y, Mao X, Zhao K, Du X, Xin J. Construction of PPARr gene knockout IPEC-J2 cell lines mediated by CRISPR/Cas technology. China animal husbandry and Veterinary medicine, 2023, 50 (07): 2670-2677. (in Chinese)
(20) Du X, Li J, Wang L,Chen C, Zhang J, Xin J. Exploration and practice of case-based teaching in the course of Veterinary Public Health. Journal of Animal Science and Veterinary Medicine, 2024, 43 (01): 63-67+70. (in Chinese)
Published books
(1) Xin Jige, Participated in Compiling the 13th Five-Year Plan for textbook of the Ministry of Agriculture, Laboratory Procedure for Animal Food Hygiene, (3rd Edition), China Agriculture Press Co., Ltd.
(2) Xin Jige, Participated in Compiling the 14th Five-Year Plan for textbook of the Ministry of Agriculture, Veterinary Public Health, (4rd Edition), China Agriculture Press Co., Ltd.
Patents
(1) Xu K, Fan M, Xin J, Xu Yang, Wu L, Yang B, Duan R, Zhang H. The utility model relates to harmless treatment of vegetable waste earthworm feeding pond. CN202122325882.7, 2022-04-26.
(2) Lai L, Xin J, Yang H, Zou Q, Fan N, Reconstruction oocyte of albino model pig and its construction method and the construction method of model pig. ZL201410438927.3, 2017-3-8.
Words for students
Look at the stars, stay grounded; look to the future, embrace your true self.